The Garden is renowned for its cactus collection, which includes more than 10,350 plants of 1,350 different taxa. Highlights of the cactus collection include:
- The subfamily Opuntioideae: The garden features the world's most complete collection of this group, displaying 208 of the 261 species and varieties recognized.
- Echinocereus: The garden displays 84 of the 91 recognized taxa.
Other major collections include
Mammillaria, Coryphantha, Ferocactus and
South American Cacti, especially
Copiapoa, Eriosyce and Echinopsis.